Evaluation of the antifungal powers of five plant species of the genus Terminalia on strains responsible for candidiasis

Background: Candidiasis is a fungal disease caused by Candida albicans, yeast that preferentially affects mucous membranes. These diseases are more and recurrent because of the generalized decline in immunity appearance resistance to classical antifungal drugs. Therefore, fighting against therapeutic failures becomes necessary. The objective this study contribute fight candidiasis through research new molecules. To do so, hydroalcoholic extracts Terminalia catappa, glaucescens, ivorensis, mantaly superba, five plant species used traditional medicine dermatoses, were tested on vitro growth resistant strains albicans. In addition, polyphenol composition these plants was carried out order evaluate their protective powers.
 Methods: tests performed solid-state dilution method. While determination polyphenols photometric method.
 Results: results showed an inhibition germs four except catappa. minimum inhibitory concentrations (MIC) obtained as follows: MIC (T. ivorensis) =0.25 mg/mL; glaucescens) =0.50 superba) = 4 mg/ML; mantaly) 2 mg/mL.
 Conclusion: This indicates T. ivorensis most active has highest content phenolic compounds. could be source effective molecules treatment candidiasis.
 Keywords: candidiasis, Terminalia, antifungal, polyphenol,